Glucophage XR (Metformin Sustained Release)

TypeDrug NameDosagePrice from 
drug typeGlucophage XR500 mg$64.99
drug typeGlucophage XR750 mg$71.99
drug typeGlucophage XR1000 mg$87.99

Generic Equivalent of Glucophage XR

TypeDrug NameDosagePrice from 
drug typeMetformin Sustained Release500 mg$33.99
drug typeMetformin Sustained Release1000 mg$35.99


Glucophage XR Information

reviewed by reviwer portrait Dr. Bolanle Aina, Pharmacist on 4/13/2021 2:19:29 PM.

How and Where to Buy Glucophage XR Online?


You can buy Glucophage XR online through our Canadian International Pharmacy at huge savings. We offer RX and OTC medications online with a valid prescription from your doctor. At Canadian Pharmacy World, your health is our priority. You can place the order online, by mail, by fax or toll-free over the telephone at 1866-485-7979.

Are There Alternative Names for the Brand and Generic Glucophage XR?


Glucophage XR (extended-release) is a diabetic medication and it comes from India also called Cetaphin XR by Aventis and United Kingdom by Merck. The generic equivalent of Glucophage XR is Metformin sustained release tablet comes from India by a different manufacturer and Canada also called Apo-Metformin ER by Apotex.

What Dosages and Forms is Glucophage XR available in?


The generic equivalent of Glucophage XR comes as a sustained release tablet in the dosage form of 1000 mg.

What is Glucophage XR used for?


Glucophage XR is indicated in addition to exercise and diet, for the treatment of type 2 diabetes in adults by improvement of blood sugar levels. Type 2 diabetes is also known as non-insulin dependent diabetes mellitus. People with type 2 diabetes are not able to make enough insulin or respond to the insulin their body makes. When this happens, sugar builds up in the blood. This can lead to serious complications including kidney damage, amputations, and blindness. Diabetes is also closely linked to heart disease. The main aim of treating diabetes is to lower the blood sugar levels to normal. Glucophage XR is metformin hydrochloride sustained-release tablet and helps to control blood sugar by making your body respond better to insulin produced naturally by the body by decreasing the amount of sugar made by liver and decreasing the amount of sugar absorbed by your intestines.

What Are The Possible Side Effects of Glucophage XR?


Some of the common side effects of Glucophage XR include nausea, diarrhea, stomach upset, gas, abdominal bloating and loss of appetite. These side effects generally fade away with time and are less bothersome when the medication is taken with meals. Glucophage XR can rarely lead to hypoglycemia (low blood sugar), especially when you drink alcohol, do not eat enough or take other medicines to lower blood sugar. In very rare cases, Glucophage XR can lead to a life-threatening side effect known as lactic acidosis, which is caused by the build-up of lactic acid in your blood. It mostly occurs in people whose kidneys do not function properly. Symptoms of lactic acidosis include weakness, unusual muscle pain, troubled breathing, unexpected stomach discomfort, nausea, vomiting, feeling cold, dizziness or light-headedness, slow or irregular heartbeat. If you experience any of these symptoms, stop taking Glucophage XR and seek medical help immediately. These are not all the possible side effects of Glucophage XR. In case of any unexpected effect, consult your healthcare professional as soon as possible.

Because Glucophage XR is an extended release tablets. You may see something that looks like the tablet in your stool. This is normal and not a cause for concern. If you have questions, talk with your doctor.

Are there any Precautions and Drug interactions for Glucophage XR?


Do not drink a lot of alcohol if you are taking Glucophage XR as this can increase your chances of getting lactic acidosis (a life-threatening condition).

Do not use Glucophage XR if you:

• Have unstable or insulin dependent diabetes (type 1 diabetes)
• Have acute or chronic metabolic acidosis (including diabetic ketoacidosis, with or without coma, history of ketoacidosis with or without coma
• Have a history of lactic acidosis (too much lactic acid in the blood)
• Drink a lot of alcohol
• Have severe liver or kidney diseases
• Are going to have an X-ray procedure with injection of iodinated contrast materials
• Suffer from dehydration (have lost a lot of water from body)
• Have a severe infection or trauma
• Are allergic to metformin hydrochloride or any of the ingredients in Glucophage XR
• Are pregnant or planning to become pregnant
• Are breast-feeding
• Have cardiovascular collapse (abrupt failure of blood circulation)
• Have surgery and during recovery phase

Before taking Glucophage XR, inform your doctor if you:

• Have cardiovascular collapse (abrupt failure of blood circulation)
• Have lactic acidosis
• Have severe liver or kidney problems
• Are 80 years old and did not have your kidney function tested
• Suffer from serious dehydration (have lost a lot of water from body)
• Have metabolic diseases such as diabetic ketoacidosis
• Drink a lot of alcohol
• Are going to have an X-ray procedure with injection of iodinated contrast materials
• Have surgery and during recovery phase
• Develop a serious medical condition such as heart attack, severe infection, stroke
• Develop or experience worsening of heart disease and heart failure
• Are pregnant or planning a pregnancy
• Are breast feeding
• Are anemic or have vitamin B12 deficiency

Drug interactions


It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs. Some medications that can interact with Glucophage XR include:

• Some other diabetic drugs such as glyburide
• Furosemide
• Nifedipine
• Cationic drugs like amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, and vancomycin
• Blood thinning agents such as phenprocoumon or other antivitamin K anticoagulants
• Diuretics, especially loop diuretics as they increase the risk of lactic acidosis by decreasing renal function
• Drugs that lead to hyperglycemia (high blood sugar) such as thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, estrogens, oral contraceptives, phenytoin, nicotinic acid, calcium channel blockers, isoniazid, beta-2-agonists
• ACE inhibitors may lower blood sugar and combination of these with Glucophage XR should be monitored carefully
• Carbonic anhydrase inhibitors like topiramate or acetazolamide

Glucophage XR Storage and Safety Information


The medication should be stored at a room temperature between 15°C and 30°C, in well closed containers. It should be kept out of sight and reach of children.

The content on this page has been supplied to canadianpharmacyworld.com by an independent third party contracted to provide information for our website. Canadianpharmacyworld.com relies on these third parties to create and maintain this information and cannot guarantee the accuracy or reliability of the information that has been provided to us.

The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.

Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We are affiliated with other dispensaries that ship product to our customers from the following jurisdictions: Canada, Singapore, New Zealand, Turkey, Mauritius, India, and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.

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Prescriptions dispensed from Canada are dispensed by: Candrug Pharmacy, ID#18985 604-543-8711. Pharmacy Manager: Carol Hou. Pharmacy Address: Unit #202A, 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9. This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
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