* The product images are for reference only. Generic equivalents may also be supplied by alternate manufacturers.
Ordering Myrbetriq (Mirabegron Extended Release)
At CanadianPharmacyWorld, we provide access to this medication for patients with a valid prescription from their healthcare provider. As a licensed pharmacy, we are committed to providing significant savings while ensuring our customers receive safe, affordable medications delivered directly to their homes. To learn more about our dedication to pharmacy standards, please visit our
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Available Brands and Generic Variants
Patients may see different brand names for this medication depending on the manufacturer and country of origin. While the active ingredient (Mirabegron) remains the same.
In Canada and Turkey, the brand (also known as Betmiga) is produced by Astellas Pharma.
Generic versions are produced by various international laboratories under different trade names:
• India: Mirago (Sun Pharma)
Dosage Strengths and Available Forms
This medication and its generic counterpart are available as 25 mg and 50 mg tablets.
Usage and Indications
This prescription medication treats symptoms of overactive bladder (OAB), such as urge urinary incontinence, urgency, and urinary frequency. It is also approved for the management of Neurogenic Detrusor Overactivity (NDO) in pediatric patients aged 3 years and older. Depending on the child's weight and ability to swallow, a healthcare provider may prescribe either the extended-release tablets or the extended-release oral suspension (granules).
Unlike traditional OAB treatments, Mirabegron belongs to a class of drugs known as beta-3 adrenergic agonists. It works by activating the beta-3 receptors in the bladder, which helps the detrusor muscle relax during the storage phase. This relaxation allows the bladder to store more urine and reduces the frequency of involuntary contractions. Take this medication exactly as prescribed by your healthcare provider.
Possible Side Effects and Adverse Reactions
Common Side Effects - If any of the following side effects persist or cause you concern, contact your healthcare provider for guidance:
• Back pain or joint pain
• Constipation
• Dizziness
• Dry mouth
• Headache
• Hypertension (increased blood pressure)
• Nasopharyngitis (inflammation of the nose and throat, which may present as cold-like symptoms such as a sore throat, nasal congestion, or cough).
• Nausea (especially in pediatric patients)
• Urinary tract infection (UTI)
Other Potential Side Effects (less common) - The following list includes side effects that are reported less frequently by individuals:
• Abdominal pain or discomfort
• Anxiety
• Diarrhea
• Fatigue
• Gastroenteritis (stomach flu symptoms, primarily in children)
• Palpitations (feeling like your heart is racing or skipping a beat)
• Sinusitis (sinus congestion or pressure)
• Tachycardia (fast heart rate)
• Tremor (shakiness)
Serious Side Effects – Although serious reactions are rare, they require immediate medical attention. Stop using the medication and call your doctor or emergency services immediately if any of the following occur:
• Angioedema: Severe swelling of the face, lips, tongue, or throat, which may cause difficulty breathing or swallowing.
• Atrial Fibrillation: New or worsening irregular heart rhythm.
• Glaucoma (Angle-Closure): Sudden eye pain, blurred vision, or seeing halos around lights.
• Kidney Stones: Severe pain in the side, back, or groin, often accompanied by blood in the urine.
• Severe Hypertension: Dangerously high blood pressure, which may present as a severe headache, chest pain, or vision changes.
• Urinary Retention: Inability to empty the bladder, a weak urine stream, or significant trouble starting to urinate.
Absolute Contraindications
Before starting treatment, it is important to identify certain medical conditions that preclude its use. Do NOT take Myrbetriq if the following conditions exist:
• Hypersensitivity: a known allergy or hypersensitivity to mirabegron or any of the inactive ingredients (such as polyethylene oxide or magnesium stearate) in the tablet or granule formulation.
• Severe Uncontrolled Hypertension: dangerously high or uncontrolled blood pressure (systolic =180 mmHg and/or diastolic =110 mmHg).
Medical Conditions Requiring Consultation
The following conditions warrant a detailed discussion with a healthcare provider before starting this medication, as they may need to be adjusted or avoided to ensure patient safety:
• Bladder Outlet Obstruction: History of significant difficulty urinating or a weak urine stream.
• Kidney Disease: Severe renal impairment or end-stage renal disease (ESRD).
• Liver Problems: Severe hepatic impairment.
• Moderate to Severe Hypertension: Pre-existing high blood pressure, as mirabegron can increase blood pressure levels.
Drug Interactions
Understanding how this medication interacts with other substances is essential for safe and effective treatment. The following medications may require close monitoring or dosage adjustments when taken concurrently:
• CYP2D6 Substrates (Desipramine, Flecainide, Metoprolol, Propafenone, Thioridazine): Mirabegron is a moderate inhibitor of the CYP2D6 enzyme. It can significantly increase the concentration of these drugs in your blood, potentially leading to toxicity.
• Digoxin (Lanoxin): Myrbetriq may increase the levels of digoxin in your system. When starting these together, your doctor may recommend starting digoxin at the lowest dose and monitoring your blood levels frequently.
Other Notable Interactions:• Antimuscarinic Medications (Solifenacin, Oxybutynin): While often used together for OAB, this combination can increase the risk of urinary retention (the inability to empty the bladder).
• Warfarin (Coumadin): While the interaction is generally minor, your healthcare provider may monitor your INR levels more closely when starting or stopping Myrbetriq.
Safety and Storage Information
This medication should be stored at room temperature away from light and moisture and out of reach of children and pets. It should not be stored in the bathroom.
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The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.
Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We are affiliated with other dispensaries that ship product to our customers from the following jurisdictions: Canada, Singapore, New Zealand, Turkey, Mauritius, India, and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.