* The product images are for reference only. Generic equivalents may also be supplied by alternate manufacturers.
Ordering Synthroid (Levothyroxine)
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What is Synthroid?
This medication is a thyroid hormone supplement used to treat hypothyroidism, a condition where the thyroid gland does not produce enough hormones naturally. It acts as a replacement for the hormone thyroxine, which is essential for regulating your body’s energy and metabolism.
The brand Synthroid (Levothyroxine) is produced and sold by BGP Pharma/Mylan in Canada, and it is also available in India under the name Thyronom by Abbott. We also provide generic levothyroxine, such as Apo-Levothyroxin, made in Canada by Apotex.
Available Strengths and Sizes
Both the brand and generic versions come in the following oral tablet strengths:12.5 mcg, 25 mcg, 50 mcg, 62.5 mcg, 75 mcg, 88 mcg, 100 mcg, 112 mcg, 125 mcg, 137 mcg, 150 mcg, 175 mcg, 200 mcg, and 300 mcg.
Adverse Reactions & Side Effects
Common Side Effects – If these persist or become a concern, please reach out to your healthcare provider:
• Most medications come with potential side effects. While Abdominal cramps
• Changes in appetite
• Diarrhea
• Flushing
• Headache
• Increased sweating
• Nervousness or tremors
• Sleep problems (insomnia)
• Weight loss
Other Potential Side Effects (less common) - The following list includes side effects that are reported less frequently by individuals:
• Changes in menstrual periods
• Emotional lability (mood swings)
• Fatigue
• Fever
• Hair loss (usually temporary during the start of treatment)
• Heat intolerance
• Muscle weakness
• Palpitations (feeling your heart race)
Serious Side Effects – These reactions are rare but require immediate medical attention. Stop using the medication and call your doctor or emergency services if you experience:
• Bone Density Loss
• Cardiovascular Events
• Hypersensitivity
• Pseudotumor Cerebri
• Thyroid Storm
Contraindications
Do NOT take this medication if any of the following conditions exist:
• Hypersensitivity: known allergy to levothyroxine sodium or any inactive ingredients in the tablet.
• Uncorrected Adrenal Insufficiency: adrenal glands that do not produce enough hormones; starting thyroid meds before treating the adrenals can trigger a dangerous adrenal crisis.
• Untreated Thyrotoxicosis: an existing excess of thyroid hormone in your body that has not yet been addressed.
Precautions & Warnings
The following conditions warrant a detailed discussion with a healthcare provider before starting this medication, as they may need to be adjusted or avoided to ensure patient safety:
• Cardiovascular Disease: Heart attack, chest pain (angina), or clogged arteries, as thyroid hormones increase the heart's workload.
• Diabetes: Diabetes mellitus or insipidus, as Synthroid can change your blood sugar levels and require insulin adjustments.
• Elderly Patients: Advanced age, which requires a lower starting dose due to increased heart sensitivity.
• Myxedema coma: A severe, emergency form of hypothyroidism that requires hospital-based IV treatment instead of tablets.
• Osteoporosis: Pre-existing low bone density, which can be worsened by excessive thyroid hormone.
Drug Interactions
Understanding how Synthroid interacts with other substances is crucial for safe and effective treatment. The following medications may need close monitoring or dosage adjustments when taken together:
• Amphetamines: Using stimulants like Adderall with thyroid hormones can overstress the heart, leading to irregular rhythms.
• Anticoagulants (Blood Thinners): Synthroid can increase the effect of warfarin, raising the risk of bleeding.
• Bile Acid Sequestrants (Cholesterol Blockers): Drugs like cholestyramine bind to Synthroid in the gut. Take these at least 4 hours apart.
• Nitrates: Increased metabolic demand from Synthroid may make chest pain medications (nitrates) less effective
• Sodium Polystyrene Sulfonate: This potassium-lowering drug can bind to and "trap" your thyroid medication, preventing absorption.
Other Notable Interactions• Antacids and Supplements: Products containing calcium, iron, magnesium, or aluminum (like Tums or Maalox) block absorption. Separate doses by at least 4 hours.
• Antidiabetic Therapy: As your metabolism improves, your need for insulin or oral meds like metformin may increase.
• Antiepileptics (Seizure Meds): Drugs like phenytoin or carbamazepine "flush" thyroid hormone out of your system faster, requiring a higher dose.
• Proton Pump Inhibitors (PPIs): Stomach acid blockers like omeprazole can hinder the tablet from dissolving properly.
• Tricyclic Antidepressants: Using medications like amitriptyline can increase the risk of heart rhythm issues.
Safety and Storage Information
Always store this medication at controlled room temperature (68°F to 77°F), away from heat, light, and moisture. Avoid storing this medication in the bathroom. It may take several weeks to notice the full effects of the treatment. Always keep medication out of the reach of children and pets.
Blog Post
What You Need to Know This Thyroid Awareness MonthThe content on this page has been supplied to canadianpharmacyworld.com by an independent third party contracted to provide information for our website. Canadianpharmacyworld.com relies on these third parties to create and maintain this information and cannot guarantee the accuracy or reliability of the information that has been provided to us.
The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.
Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We are affiliated with other dispensaries that ship product to our customers from the following jurisdictions: Canada, Singapore, New Zealand, Turkey, Mauritius, India, and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.