Buy Zestoretic (Lisinopril/HCTZ)

TypeDrug NameDosagePrice from 
drug typeZestoretic20 mg/12.5 mg$197.99

Generic Equivalent of Zestoretic

TypeDrug NameDosagePrice from 
drug typeLisinopril/HCTZ10 mg/12.5 mg$51.99
drug typeLisinopril/HCTZ20 mg/12.5 mg$61.99
drug typeLisinopril/HCTZ20 mg/25 mg$77.99


Zestoretic Information

reviewed by reviwer portrait Dr. Bolanle Aina, Pharmacist on 7/27/2021 9:58:10 AM.

How and Where to Buy Zestoretic Online?


You can buy Zestoretic online through our Canadian International Pharmacy at huge savings. We offer RX and OTC medications online with a valid prescription from your doctor. At Canadian Pharmacy World, your health is our priority. You can place the order online, by mail, by fax or toll-free over the telephone at 1866-485-7979.

Are There Alternative Names for the Brand and Generic Zestoretic?


Zestoretic is a blood pressure medication that comes from Canada and is manufactured by AstraZeneca. The generic equivalent of Zestoretic is lisinopril/hydrochlorothiazide and it comes from United Kingdom by a different manufacturer and Canada also called Sandoz Lisinopril HCT manufactured by Sandoz.

What Dosages and Forms is Zestoretic available in?


The brand Zestoretic is available as tablets in the dosage forms of 10 mg/12.5 mg, 20 mg/12.5 mg and 20 mg/25 mg. the generic equivalent of Zestoretic (lisinopril/hydrochlorothiazide) is available in the dosage forms of 10 mg/12.5 mg, 20 mg/12.5 mg and 20 mg/25 mg.

What is Zestoretic used for?


Zestoretic is used to lower high blood pressure. Zestoretic contains a combination of 2 drugs, lisinopril and hydrochlorothiazide. Lisinopril is an angiotensin converting enzyme (ACE) inhibitor. You can recognize ACE inhibitors because their medicinal ingredient ends in “pril”. It helps to lower the blood pressure. Hydrochlorothiazide is a diuretic or “water pill” that increases urination. This helps to lower blood pressure. Zestoretic does not cure high blood pressure. It helps to control it. Hence, it is important to continue taking the medicine even if you feel fine. Take Zestoretic exactly as prescribed by your doctor. It is recommended to take the dose at the same time every day. This medication can be taken with or without food. If it upsets stomach, take it with food or milk.

What Are The Possible Side Effects of Zestoretic?


Some of the common side effects of Zestoretic include dizziness, headache, cough, drowsiness, fatigue, weakness, rash, abdominal pain, upset stomach, decreased appetite, constipation, muscle pain or cramp, and abnormal blood test results. Other serious side effects of this medication include low blood pressure, dizziness, fainting, light-headedness, decreased or increased levels of potassium in the blood, irregular heartbeats, muscle weakness, allergic reaction with symptoms of rash, hives, swelling of the face, lips, tongue or throat, difficulty swallowing or breathing. These are not all the possible side effects of Zestoretic. In case of any unexpected effect, consult your healthcare professional as soon as possible.

Are there any Precautions and Drug interactions for Zestoretic?


Hydrochlorothiazide in Zestoretic can cause sudden eye disorders such as myopia or glaucoma. If untreated, it can lead to permanent loss of vision.

You may become sensitive to the sun while taking Zestoretic. Exposure to sunlight should be minimized until you know how you respond.

Zestoretic can cause dizziness, light-headedness or fainting especially after the first dose or the dose is increased. Before you drive or operate machinery, know how you respond to this medication.

Do not use Zestoretic if you:

• Are allergic to lisinopril, hydrochlorothiazide or any other ingredient in the medication
• Are allergic to any sulfonamide-derived drugs (Sulfa drugs)
• Have experienced allergic reaction with itchiness, hives, dizziness, swelling of hands, feet, or ankles, face, lips, tongue, throat or sudden difficulty in breathing or swallowing to any ACE inhibitor
• Are already taking a blood pressure-lowering medication that contains aliskiren (such as Rasilez) and have conditions such as kidney disease, diabetes, high potassium levels, heart failure combined with low blood pressure
• Are taking an angiotensin receptor blocker (ARB) or another medicine used to treat high blood pressure or another ACE inhibitor and have conditions such as diabetes with end organ damage, high potassium levels, kidney disease, heart failure combined with low blood pressure
• Have been diagnosed with hereditary angioedema which can be triggered by different factors such as surgery, flu or dental procedures
• Are taking Entresto (sacubitril/valsartan) due to the increased risk of serious allergic reaction which causes swelling of face or throat
• Have certain kidney disease or have difficulty urinating or produce no urine
• Are pregnant or planning to become pregnant. This medication taken during pregnancy can cause injury and even death to your baby
• Are breastfeeding. Zestoretic passes into breast milk

Before taking Zestoretic, inform your doctor if you:

• Have experienced an allergic reaction to any drug used to lower blood pressure or penicillin
• Have recently received or are planning to get allergy shots for bee or wasp stings or have an allergy
• Have narrowing of an artery or heart valve
• Have had a heart attack or stroke
• Have heart failure
• Have diabetes, liver or kidney disease
• Have lupus, gout, or asthma
• Are dehydrated or suffer from excessive vomiting, diarrhea, or sweating
• Are taking a salt substitute that contains potassium, potassium supplements, or a potassium sparing diuretic (water pill)
• Are taking a medicine that contains aliskiren, such as Rasilez, used to lower high blood pressure
• Are taking an angiotensin receptor blocker (ARB)
• Are on a low salt diet
• Are on dialysis
• Are receiving gold (Sodium aurothiomalate) injections
• Are less than 18 years old
• Are on LDL apheresis (A treatment to lower the LDL cholesterol in the blood)
• Are taking drugs such as Temsirolimus and everolimus (used to treat cancer), sirolimus (used to prevent organ rejection after a transplant), a neutral endopeptidase inhibitor

Drug interactions


It is important to tell your healthcare professional about all other medicines that you have taken recently including any kind of supplements and non-prescription drugs. Some medications that can interact with Zestoretic include:

• Adrenocorticotropic hormone (ACTH) used to treat nephrotic syndrome and in diagnostic tests
• Alcohol, barbiturates (sleeping pills), or narcotics (strong pain medications)
• Amantadine used to treat the flu and reduce symptoms of Parkinson’s disease
• Amphotericin B, an antifungal drug
• Antacids
• Drugs used to treat cancer (such as cyclophosphamide), methotrexate, temsirolimus and everolimus)
• Antidepressants, in particular selective serotonin reuptake inhibitors (SSRIs), including citalopram, escitalopram, and sertraline
• Drugs to treat diabetes such as Insulin, Oral medications (like sulphonylureas)
• Bile acid resins used to lower cholesterol
• Blood pressure-lowering drugs, including diuretics (“water pills”), aliskiren-containing products (e.g.Rasilez), diazoxide, methyldopa and beta blockers such as atenolol, metoprolol, propranolol, calcium channel blockers such as felodipine, amlodipine, nifedipine, and angiotensin II receptor blockers such as candesartan, valsartan, losartan.
• Calcium or vitamin D supplements
• Capsaicin, an ingredient in some creams used to relieve arthritis pain
• Corticosteroids used to treat joint pain and swelling
• Cyclosporine used to treat autoimmune diseases
• Digoxin, a drug used to treat heart conditions, or other medicines to control the rhythm of your heart
• Drugs that slow down or speed up bowel function, including atropine, biperiden, domperidone and metoclopramide
• Drugs used to treat epilepsy, including carbamazepine and topiramate
• Gold (sodium aurothiomalate), used to treat auto-immune conditions such as rheumatoid arthritis and psoriatic arthritis
• Gout medications, including allopurinol and probenecid
• Lithium, a medicine to treat bipolar disease
• Drugs that can cause low blood potassium levels (hypokalemia) such as Laxatives, Corticosteroids (such as prednisone), Salicylic acid derivatives
• Nonsteroidal anti-inflammatory drugs (NSAIDs), used to reduce pain and swelling
• Drugs that can increase blood potassium levels (hyperkalemia) such as Potassium supplements, Salt substitutes
• Rituximab used to treat cancer, transplant rejection, and some autoimmune diseases
• Sirolimus, a drug used to prevent organ rejection after a transplant
• Skeletal muscle relaxants used to relieve muscle spasms, including tubocurare
• Tetracycline antibiotics
• Tissue plasminogen activator (TPA) that is used to dissolve blood clots that have formed in blood vessels

Zestoretic Storage and Safety Information


The medication should be stored at a temperature between 15°C and 30°C, in a tightly closed container, protected from light. It should be kept out of sight and reach of children.

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The content on this page has been supplied to canadianpharmacyworld.com by an independent third party contracted to provide information for our website. Canadianpharmacyworld.com relies on these third parties to create and maintain this information and cannot guarantee the accuracy or reliability of the information that has been provided to us.

The drug information provided here is only a summary and does not contain all the list of possible side effects and drug interactions regarding this medication. Be sure to contact your doctor or pharmacist if you have any specific question or concern. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a healthcare professional.

Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We are affiliated with other dispensaries that ship product to our customers from the following jurisdictions: Canada, Singapore, New Zealand, Turkey, Mauritius, India, and United Kingdom. The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with our authorized dispensaries that procure product through reliable sources.

Similar Drugs in the category of Blood-Pressure-Medications-(Angiotensin-Converting-Enzyme):

   Zestril    Prinivil    Vasotec    Altace    Aceon

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Prescriptions dispensed from Canada are dispensed by: Candrug Pharmacy, ID#18985 604-543-8711. Pharmacy Manager: Carol Hou. Pharmacy Address: Unit #202A, 8322-130th Street, Surrey, British Columbia, Canada V3W 8J9. This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
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