The Truth About Cooking Oils and Inflammation: What Science Reveals

written by Dr. Bolanle Aina - Oct 27, 2025

Cooking oil is an ingredient we reach for without thinking twice; it’s essential in creating nearly every dish you love. But this kitchen staple is also surrounded by misinformation and enduring myths. It's critical to ensure the oil you consume is truly safe, healthy, and optimized for your cooking methods.

There’s a lot of debate about cooking oils. Some oils are considered to be heart-healthy, while others are blamed for fueling disease. A significant part of the controversy centers on inflammation.

Inflammation is a process linked to chronic conditions, including arthritis, diabetes, and heart disease. So, is your cooking oil contributing to inflammation? What does science actually say about the oils we use in our kitchens? Let’s find out.

The Science of Inflammation

Inflammation is the body’s built-in defense mechanism. When you sprain an ankle or get a cut, your body sends immune cells to the injured area. This process is known as acute inflammation, and it causes swelling, redness, and heat. Therefore, inflammation is an essential part of the body's recovery process, signaling that healing is underway.

However, inflammation sometimes extends beyond the healing process. Chronic inflammation persists in the body, causing diseases to develop in the background. Over time, the inflammation grows and compounds. This is the type of inflammation we are generally worried about.

Acute vs. Chronic Inflammation

Acute inflammation: Short-term, protective, and necessary for recovery.

Chronic inflammation: Long-term, often causing damage. It lingers quietly and is linked to conditions like type 2 diabetes, cardiovascular disease, and even certain cancers.

Common Triggers of Chronic Inflammation

The transition from acute inflammation (regular and temporary) to chronic inflammation (persistent and damaging) is often driven by prolonged unhealthy lifestyle factors:

• Diets high in processed foods and sugar

• Excessive intake of unhealthy fats

• Sedentary lifestyle

• Chronic stress

• Poor sleep

Did You Know? Chronic inflammation is sometimes referred to as a “silent killer” because it often develops asymptomatically, escalating to serious health problems before being detected. Since chronic inflammation lacks the clear signs of heat, redness, and swelling characteristic of acute inflammation, its symptoms are often subtle and persistent, including general fatigue, joint pain, digestive problems, and recurring skin issues. These low-grade, systemic symptoms are often easily mistaken for normal aging or stress and are typically managed with anti-inflammatory medications.

Cooking oils are more than just a means of making the perfect sauce. At their core, they’re made up of fatty acids, and these play a much bigger role in your health than most people realize. Fatty acids are essential building blocks that maintain bodily functions by ensuring cell membranes are flexible and receptors communicate efficiently.

Healthy fats from cooking oils provide energy and support your brain and nervous system. They can even help regulate hormones. Perhaps most importantly, fatty acids have a direct influence on inflammation.

Where it gets tricky is that oils can either soothe or spark inflammation, depending on the type and balance of the fatty acids consumed.

Pro-Inflammatory vs. Anti-Inflammatory Oils

Not all oils have the same effect on your body. Some, especially those high in omega-6 fatty acids, such as soybean, corn, cottonseed and sunflower oils, can trigger inflammation in the body when consumed in excess.

On the other hand, oils rich in omega-3s or monounsaturated fats, such as flaxseed oil, olive oil, walnut oil and avocado oil, tend to have the opposite effect, helping to calm inflammation and protect your long-term health. Moreover, oils that have a mix of omega-6 and monounsaturated fats, such as canola oil, peanut oil and sesame oil, have moderate to neutral effect on inflammation.

The takeaway isn’t that you should fear one type of oil and worship another. It’s about balance. The impact of cooking oils depends largely on how much you use and how well you balance your intake of different fatty acids. When oils are chosen thoughtfully and used in moderation, they can be a valuable part of an anti-inflammatory diet.

Omega-6 Fatty Acids and Inflammation

Omega-6 fatty acids are a type of essential fat. Your body can’t make them on its own, and you have to get them from food. The most common omega-6 in our diets is linoleic acid, and it’s found in many everyday cooking oils like soybean, sunflower, corn, and safflower oil. You’ll also find omega-6s in nuts and seeds, which are generally healthy sources. The major type of omega-6 is linoleic acid.

The Double Role of Arachidonic Acid

When you eat linoleic acid, your body can convert some of it into another fatty acid called arachidonic acid. This is where things get a little complicated. Arachidonic acid can fuel inflammation, but it can also help alleviate it.

On one hand, arachidonic acid helps your body produce molecules that trigger inflammation. This is actually useful when you’re fighting off an infection or trying to heal from an injury. Without this process, your body wouldn’t be able to protect itself.

On the other hand, arachidonic acid also produces compounds that resolve inflammation, signaling your body to cool things down once the threat has passed. This is just as important because staying “switched on” in inflammation mode damages healthy tissues.

The Role of Omega-3 Fatty Acids

If omega-6s are the spark that can light inflammation, then omega-3s are the water that helps keep the flames under control. These fatty acids are recognized for their potent anti-inflammatory properties, and they help you maintain long-term health.

Omega-3s help your body in ways that go far beyond fighting inflammation. They:

• Support brain health and improve mood

• Protect your heart by lowering triglycerides and blood pressure.

• Reduce joint stiffness and pain linked to arthritis.

• Promote eye health and healthy skin.

One of their most important jobs, though, is counterbalancing the effects of omega-6s. When your body has enough omega-3s available, it can shift toward producing more anti-inflammatory compounds, which help restore balance after inflammation has done its job.

The Balance Between Omega-6 and Omega-3

You don’t have to choose one type of fat and avoid the other. You would not be able to do it, because they are often sprinkled into our everyday diet without our knowledge. Your body needs both omega-6 and omega-3 fatty acids to function well.

The key is in the ratio. Today, many diets hover around 15:1 or even higher and create an imbalance that fuels chronic inflammation. Your goal is to aim between 1:1 and 1:4.

This doesn’t mean you should cut out omega-6s completely. Instead, focus on adding more omega-3-rich foods to your diet to bring the ratio back into balance.

Choosing the Right Cooking Oils

Now that you know the difference between good oil and somewhat bad oil, and how to balance them, you can make your choices. By the way, no single oil is perfect for every situation. Each one has its strengths, depending on its fatty acid profile and its stability when heated. Understanding these differences can help you select the appropriate oil for the intended purpose.

Types of Cooking Oil

Most cooking oils fall into a few main categories:

Monounsaturated fats (MUFAs): Found in olive oil, avocado oil, and peanut oil. These fats are heart-healthy and generally anti-inflammatory.

Polyunsaturated fats (PUFAs): Found in oils like soybean, corn, sunflower, and flaxseed. They contain both omega-6 and omega-3 fatty acids, so their effects on inflammation depend on the balance between these two types of fatty acids.

Saturated fats: Found in coconut oil, palm oil, and butter. These are more heat-stable, but should be used in moderation, as high intakes are associated with an increased risk of heart disease.

Best Cooking Oils for Different Needs

Avocado oil: With one of the highest smoke points (around 500°F/260°C), it is excellent for roasting, stir-frying, or grilling. It’s also rich in monounsaturated fats, which support heart health and help keep inflammation in check.

Extra-virgin olive oil: Packed with antioxidants and healthy monounsaturated fats, EVOO is ideal for drizzling over salads, dipping bread, or finishing cooked dishes. Its smoke point is lower than that of avocado oil, so it’s best suited for low- to medium-heat cooking.

Coconut oil: Stable at high temperatures, it is commonly used in baking or sautéing. While it’s less likely to oxidize during cooking, it is high in saturated fat, so moderation is key.

Flaxseed oil: A superstar for omega-3 content, but not suitable for heating. Use it in smoothies, salad dressings, or drizzle it over cooked vegetables to get its anti-inflammatory benefits.

Canola oil: A versatile, budget-friendly option with a moderate amount of omega-3s and a fairly high smoke point. Works well for baking, frying, or everyday cooking.

Variety is Key. Instead of relying on just one oil, keep a mix in your kitchen. Avocado oil can meet your high-heat cooking needs, while olive oil is ideal for adding flavor and antioxidants to cold or lightly cooked dishes. Adding in flaxseed or walnut oil occasionally can boost your omega-3 intake.

You may be asking, 'Is organic oil really worth the premium?' The answer is yes. Whenever possible, choose certified organic, cold-pressed oils. Conventional oils may contain pesticides and herbicides, solvent residues, trans fat and other products of heavy industrial processing, which may further fuel inflammatory responses in the body.

The Importance of Moderation

Even though oils can provide important fatty acids and health benefits, it’s easy to forget that they are also very calorie-dense. Just one tablespoon of any oil contains about 120 calories, and those calories can add up quickly if you’re not mindful. This doesn’t mean you should fear oils, but it does mean they should be used thoughtfully.

Instead of pouring oil freely into the pan, try measuring it out or using a spray to lightly coat your food. Another trick is to combine oils with water or broth when sautéing vegetables, allowing you to use less oil without sacrificing flavor.

The bigger picture, though, is about balance. Oils should be paired with a variety of fresh foods, including colorful vegetables, leafy greens, beans, whole grains, fruits, nuts, and lean proteins. Oils can enhance these foods by helping your body absorb fat-soluble vitamins (such as A, D, E, and K), but they work best as part of a nutrient-rich diet rather than the main ingredient.

Conclusion

Cooking oils aren’t simply good or bad. They are complex, and their impact depends on the type of oil, the amount used, and what else is on your plate. Oils rich in monounsaturated fats and omega-3s, such as olive, avocado, and flaxseed oil, can help combat inflammation, especially when balanced with fewer highly processed, omega-6-heavy oils.

The key takeaway is moderation and balance. Select oils that suit your cooking style and rotate them to achieve a variety of flavors. That way, you can enjoy flavorful meals while providing your body with the necessary nutrients and simultaneously manage inflammation. For personalized dietary guidance tailored to your specific health goals or conditions, always consult a registered dietitian or certified nutritionist for expert advice.

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DISCLAIMER

While the above article is based on thorough research, we do not claim to offer a substitute for medical advice from a qualified healthcare provider. The article was written for information and educational purposes only. We aim to provide helpful information to our readers, but cannot provide a treatment, diagnosis, or consultation of any sort, and we are in no way indicating that any particular drug is safe or appropriate for you and your individual needs. To receive professional medical attention, you must see a doctor.